Tesofensine Capsules 500mcg x 30 caps

Tesofensine Capsules 500mcg x 30 caps – Premium Research-Grade

Buy Tesofensine Capsules 500mcg x 30 caps and experience one of the most potent research compounds for supporting weight loss, boosting energy, improving mood, and enhancing cognitive performance. Tesofensine Capsules 500mcg contain a powerful triple reuptake inhibitor that increases serotonin, norepinephrine, and dopamine levels—neurotransmitters directly linked to appetite regulation, energy metabolism, and mental clarity.

Research suggests Tesofensine Capsules 500mcg can help reduce appetite, increase fat oxidation, and improve metabolic rate, leading to significant reductions in body weight and body fat. Clinical trials have shown that participants taking 0.25 mg to 1 mg daily achieved average weight losses of 6.7–12.8 kg in just 24 weeks—far exceeding results from many approved anti-obesity medications.

Beyond weight management, Tesofensine Capsules 500mcg x 30 caps have shown promise in supporting cognitive health, improving focus, elevating mood, and boosting motivation. Studies indicate benefits for those with attention-related disorders, sleep challenges, and even metabolic imbalances such as poor insulin sensitivity. Some research also suggests Tesofensine may support sexual health and recovery from eating-related disorders.

For research purposes, Tesofensine Capsules 500mcg offer a balanced dose—high enough to deliver measurable results while minimizing side effects observed at higher doses. Most studies recommend 0.25–0.5 mg daily for optimal benefit-to-tolerance ratio.

Our Tesofensine is lab-verified for purity using advanced testing methods, including RP-HPLC, and delivered in sterile, sealed capsules for maximum stability. Each batch is backed by a Certificate of Analysis, ensuring consistent quality and potency for your research needs.

Key Benefits from Research:

• Supports significant weight loss and fat reduction

• Promotes appetite suppression and satiety

• Enhances energy, mood, and motivation

• Supports cognitive clarity and focus

• May help regulate blood sugar and improve insulin sensitivity

• Backed by multiple peer-reviewed clinical trials

Experience research-grade quality you can trust—order Tesofensine Capsules 500mcg x 30 caps today and explore its potential in your laboratory studies.

B. Improves Cognitive Health

Emerging research suggests that tesofensine may play a valuable role in preserving cognitive health by indirectly enhancing cholinergic neurotransmission — the process by which nerve cells communicate with each other. This mechanism is closely linked to improved performance in key brain functions, including learning, memory retention, and problem-solving skills. By supporting these pathways, tesofensine shows potential in addressing neurodegenerative conditions such as Alzheimer’s and Parkinson’s disease.

Scientific Evidence Supporting Cognitive Benefits

• Early Clinical Trials in Alzheimer’s Disease: Two small, 4-week Phase IIa clinical studies in patients with mild Alzheimer’s disease reported significant improvements in cognitive function following tesofensine treatment, highlighting the need for larger Phase III trials for confirmation. [25–26]

• Anti-Obesity Effect and Cognitive Protection: Obesity has been increasingly recognized as a major risk factor for cognitive decline, particularly in older adults. [27–30] By promoting weight loss, tesofensine may indirectly help safeguard against obesity-related cognitive impairment.

• Reduction of Amyloid Beta in Alzheimer’s Models: In an Alzheimer’s mouse model, tesofensine administration lowered brain concentrations of amyloid beta — abnormal protein aggregates widely considered a key driver of the disease’s progression. [31]

• Parkinson’s Disease Symptom Improvement: In patients with advanced Parkinson’s disease experiencing motor fluctuations, low-dose tesofensine improved daily living activities and enhanced motor function. [32]

These findings collectively point toward tesofensine’s dual potential — both as a cognitive health protector and as a supportive treatment avenue for serious neurodegenerative disorders. While additional large-scale studies are needed, the current evidence is promising and paves the way for future therapeutic applications.

C. Improves Mood

The mood centers of the central nervous system have also been shown to be positively affected by tesofensine. Sustained treatment with tesofensine has been shown to improve overall mood through its antidepressant effect. Studies show that tesofensine affects mood by:

1. Increasing the levels of brain-derived neurotrophic factor (BDNF), thereby triggering an antidepressant effect. [33]
2. Triggering an anti-anxiety effect in obese individuals with comorbid depression and anxiety symptoms. [34]
3. Increasing the levels of the neurotransmitters serotonin, noradrenaline, and dopamine. [35]

D. Improves Blood Sugar Levels

Tesofensine has also been found to have beneficial effects on blood sugar. By promoting weight loss, tesofensine may indirectly contribute to improving insulin sensitivity in individuals with obesity or overweight. Insulin sensitivity refers to the body’s ability to respond to the effects of insulin, a hormone that acts as a key to unlocking cells, thus allowing glucose (blood sugar) from the bloodstream to enter and be utilized by cells for energy production. Weight loss also plays a significant role in reducing blood sugar levels and decreasing the incidence of type II diabetes.

Clinical trials have shown that weight loss drugs such as tesofensine demonstrate efficacy in improving blood sugar levels:

1. In obese patients, administration of tesofensine at varying doses (0.25 mg, 0.5 mg, and 1.0 mg) resulted in a reduction in blood sugar levels and improvement in quality of life with significant results observed in the highest dose groups. [36]
2. In rodents, tesofensine also induced a significant reduction in blood sugar levels in addition to weight loss. [37-38]

E. Increases Energy Levels

Tesofensine treatment is also beneficial in improving one’s productivity by increasing energy levels. Medical weight loss programs with this medication can cause a significant increase in energy levels by having the following positive results: reduced appetite with balanced nutrition, increased physical activity, increased metabolism resulting in more calories being burned, and hormonal balance. Evidence supports the energy-boosting effects of tesofensine:

1. A study found that tesofensine can boost energy by increasing the levels of the neurotransmitters dopamine and norepinephrine, which help regulate energy balance, motivation, interest, and drive. [35]
2. The administration of tesofensine in overweight and moderately obese men induced higher energy expenditure compared to placebo. [39]

F. Treats Sexual Dysfunction

Because of its potent antidepressant effect, tesofensine has also been studied for its therapeutic benefits on sexual dysfunction, according to studies:

1. Tesofensine has the capacity to increase the levels of dopamine, a neurotransmitter that contributes to the desire for sexual activity, erection, and ejaculation, making it beneficial for patients with sexual dysfunction related to dopamine deficiency. [35]
2. Tesofensine administration is effective in treating depression-related sexual dysfunction, suggesting that it can help ramp up sexual power. [40]

G. Treats Eating Disorders

Studies reported that triple reuptake inhibitor such as tesofensine also holds therapeutic potential for eating disorders:

1. In obese patients, tesofensine administration reduced their desire to eat and resulted in a significant increase in their satiety levels after 14 days of treatment without adverse events. [8]
2. In patients with binge eating disorder, a condition in which a person eats large quantities of food when stressed, tesofensine administration has been shown to improve its symptoms, possibly due to tesofensine’s potent antidepressant effect, without an adverse event. [41-44]
3. In the diet-induced obese rat, tesofensine induced appetite suppression by indirect stimulation of α1 adrenoceptor and dopamine d1 receptor pathways. [45]

H. Treats Attention-Deficit/Hyperactivity Disorder (ADHD)

ADHD is characterized by short attention span, hyperactivity, and impulsivity, and is common in children and even adults. Evidence suggests that tesofensine may have beneficial effects on this mental condition:

1. Studies show that ADHD is strongly linked with low levels of dopamine and serotonin and that tesofensine can have beneficial effects on this condition by increasing the levels of these neurotransmitters. [46-48]
2. A study reported that tesofensine can lower the risk of ADHD associated with obesity. [49]

I. Improves Sleep Quality